About Histamine analysis
Histamine can be found in aquaculture and fishing products. The presence of this substance is the result of post-mortem degradation due to microbiological activity; hence it is an index of improper products storage. Histamine fish poisoning is among the most common toxicities related to fish ingestion; it resembles an allergic reaction but is actually caused by bacterially generated toxins in the fish tissues. Typical manifestations of histamine fish poisoning include rash, flushing, gastrointestinal complaints, and headache.
In the European Union, sampling and analysis performance for the detection of histamine in fish commodities are ruled by the Commission Regulation (EC) No 1441/2007 amending Regulation (EC) No 2073/2005 and by Commission Regulation (EU) No 1019/2013 amending Annex I to regulation No 2073/2005.